The Europa League returns with the potential for drama at every turn. We've previewed each group so you don't have to.
Manchester City vs Juventus (Group A) immediately jumps out at you as a must-watch clash but there's plenty of other match-ups worth taking note of.
Holders Atletico Madrid, who lost their opening match in the competition, face a tough home tie against fomer Champions League finalists Bayer Leverkusen (Group B).
There's also another Spanish-German clash in Group J as Sevilla are at Borussia Dortmund.
Meanwhile, Liverpool head to Holland to play Utrecht with boss Roy Hodgson promising to make up for last week's Carling Cup debacle.
Here are the Group Previews:
Group A
Manchester City at home to Juventus is the pick of Thursday's Europa League matches for a number of reasons. For one, there has been a lot of talk between the two sides ahead of the clash.
Juventus' Marco Motta did not do himself any favours in Manchester by declaring that City are "proof of how big-name signings and big spending are not enough to obtain great results."
One of those expensive new arrivals that Motta talked about is Jerome Boateng, who manager Roberto Mancini is debating whether or not to hand the Germany star his first start against Juventus at Eastlands.
Adding more spice to what should be an entertaining contest, Mancini has openly said he used to support Juve as a boy but that Thursday's match won't be a special occasion for him.
Juve go into this encounter with a poor defensive record but boss Luigi Del Neri remains confident his side can get the result they need following their opening round draw with KKS Lech Poznan.
The Polish side play FC Salzburg next.
Manchester City vs Juventus Preview
Lech Poznan vs FC Salzburg
Group B
Atletico Madrid did not get their defence of the Europa League off to a good start when they came away form Greece as shock 1-0 losers to a team many pundits might struggle to spell. Aris Thessaloniki FC did themselves proud that night but do not expect the same lethargic performance from Atletico on Thursday as they host German side Bayer Leverkusen.
Quique Sanchez Flores' men have actually started the season well - they beat Inter Milan in the UEFA Super Cup - and are currently fifth in the Spanish La Liga after five rounds.
Bayer Leverkusen, who smashed Rosenborg BK 4-0 in their opening Group B match, might still fancy coming away from Spain with at least point, especially with ex-Real Madrid manager Jupp Heynckes' knowledge of Spanish football at their disposal.
Atletico will be without new centre-back Diego Godin, because of a knee injury.
In the other clash Greek conquerors of Atletico, Aris have the chance to take Group B by the scruff of the neck by winning against Rosenborg. Aris have never lost at home in Europe - a run now at 22 games - but they will have to get a result in Norway.
Atletico vs Leverkusen Preview
Rosenborg vs Aris Preview
Group C
Portuguese giants Sporting are in bad shape at the moment. Their hunt for another domestic title has descended into mid-table scraps but the good news is the Europa League can provide a welcome distraction as well as a platform for them to save their season.
Sporting got their Europa campaign underway with a notable 2-1 win away to French side Lille. They entertain PFC Levski Sofia knowing that a win against the Bulgarians will put them in pole position to top Group C.
Sporting's preparations for the game have been completed against the background of the news that they will be without midfielder Pedro Mendes until November after he underwent surgery to repair a knee tendon injury earlier this week.
Levski can also go top with a win after they beat KAA Gent 3-2 in the last round. Ahead of Thursday's fixtures, Gent manager Francky Dury has played down the significance of his side's Europa League meeting with fellow opening round losers Lille.
Sporting vs Levksi Sofia Preview
Gent vs Lille Preview
Group D
Dinamo Zagreb's true standing in the competition will be known on Thursday when they travel to Greece to play PAOK. Zagreb's 2-0 win against Villareal was impressive but translating that type of performance outside of Croatia will be a more trickier task for them.
Coach Vahid Halilhodzic has already warned his players they will have to handle a hostile Greek welcome.
Villarreal on the other hand can look forward to a very winnable home tie against Club Brugge who drew 1-1 with PAOK in their first match. Their manager Juan Carlos Garrido has outlined what he expects from his players by saying: "we need to win because to get through we need to get more than 10 points."
PAOK vs Dinamo Zagreb Preview
Villarreal vs Club Brugge Preview
Group E
AZ Alkmaar got an important three points at home to FC Sheriff in the last round of fixtures. The Dutch outfit have an appalling away record in European matches and midfielder Eric Falkenburg is expecting a tough test against Belarusian champions BATE Borisov.
Meanwhile, it will be a reunion of sorts when Moldovan champions Sheriff host big Ukrainian side Dynamo Kiev.
Sheriff coach Andrei Sosnitski has previously gone toe-to-toe with Valeri Gazzaev on the pitch during their playing days in the former Soviet Union.
BATE Borisov vs AZ Alkmaar Preview
FC Sheriff vs Dynamo Kiev Preview
Group F
Palermo manager Delio Rossi has revealed he intends to give Fabrizio Miccoli his comeback against Lausanne in their Europa League Group F encounter. Miccoli is recovering from ankle surgery and is a key make-up of the Palermo attack - his inclusion in the team has been acknowledged by opponents Lausanne.
Sparta Prague, who last beat Palermo 3-2 at home, will be aiming for top spot in Group F when they travel to CSKA Moscow.
Czech defender Erich Brabec has warned his side to be wary of CSKA striker Vagner Love, who has scored over 100 goals in less than 200 games for the Russians.
Palermo vs Lausanne Preview
CSKA Moscow vs Sparta Prague Preview
Group G
Anderlecht defied their good form in the Jupiler League when they lost 3-1 at home to Zenit St Petersburg in their Europa League Group G clash. The result casts doubts over the Belgium outfit's ability to qualify to the next round from the group, especially if they do not get a result on Thursday against Hajduk Split.
Manager Herman van Holsbeeck believes that with a tough double-header against the Greeks AEK Athens coming up, defeat at the Stadion Puljid tomorrow will leave his side with a big mountain to climb to progress.
However, the Greek side have their own problems and are in turmoil following manager Dusan Bajevic resignation from his position at the weekend after AEK's second loss of the season which saw them plummet to 13th in the Greek Super League.
Zenit coach Luciano Spalletti has warned his side not to underestimate the wounded Greeks.
Hajduk Split vs Anderlecht Preview
Zenith vs AEK Athens Preview
Group H
Stuttgart are yet another team who will welcome the distraction of the Europa League after a shocking start to their dometic season. Christian Gross's men are bottom of the Bundesliga on the back of a 4-1 thrashing at home to Bayer Leverkusen at the weekend.
Gross still expects his team to get maximun points from the Europa League Group H away match in Denmark at Odense BK. The Germans started the group well by beating Young Boys 3-0.
Young Boys may be finding it tough going now after their Champions League dreams were ended by Tottenham Hotspur but a home win against Getafe might give them the boost needed to qualify from this group.
Getafe coach Michel has a number of absentees to cope with as his side travel to Switzerland to play Young Boys.
Odense BK vs Stuttgart Preview
Young Boys vs Getafe Preview
Group I
Sampdoria and Debrecen meet in Italy on Thursday with both teams yet to register a win in Group I. A lack of goalscoring has been Samp's main problem, but attacking pair Antonio Cassano and Giampaolo Pazzini are available to start.
Have the mind games started in Group I? Underdogs Metalist Kharkiv has publicly hailed PSV Eindhoven as Holland's number one team ahead of their clash.
PSV last won the Eredivisie title in 2008, and have finished fourth and third in the campaigns since then.
Sampdoria vs Debrecen Preview
Metalist vs PSV Preview
Group J
The pressure is already on new Sevilla coach Gregorio Manzano as he tries to pick up a side low on confidence for a tough trip to in-form Borussia Dortmund.
Sevilla need a result on Thursday after they lost their opening Group J clash 1-0 to Paris St Germain in the Europa League.
Manzano was quick to warn fans against expecting instant results, saying "I'm not the Wizard of Oz."
Meanwhile, French side PSG will be able to call on midfielder Stephane Sessegnon for the clash with Karpaty Lviv.
Borussia Dortmund vs Sevilla Preview
Paris St Germain vs Kaparty Lviv Preview
Group K
Roy Hodgson believes Liverpool striker Fernando Torres has overcome his injury troubles and is raring to go. He has recalled the Spanish World Cup winner for their Europa League fixture against FC Utrecht, as Liverpool try to get their first win in four matches.
Hodgson was in bullish mood before the game, declaring that the Reds would do their best to win the Europa League following last week's embarrassing Carling Cup exit. Hodgson famously nearly won this same competition when he was manager of Fulham last season.
FC Utrecht coach Ton du Chatinier agreed that Liverpool pose far tougher opposition than the Celtic team they beat to qualify for the group stages of the Europa League.
Napoli travel to Romania to meet Steaua Bucharest who have hired new coach Marius Lacatus.
Lacatus accepted an offer to return to the club for a third spell after Ilie Dumitrescu resigned last week following criticism from the club's supporters.
In the opening round of Group K, Liverpool strolled to a 4-1 win over Steau at Anfield while Napoli and Utrecht played out a goalless draw in Italy.
FC Utrecht vs Liverpool Preview
Steaua Bucharest vs Napoli Preview
Group L
Former holders, Porto hammered Rapid Vienna 3-0 in their opening game in the competition, but there has been a flurry of team news for their next match at CSKA Sofia.
Fredy Guarin, Cristian Rodriguez, James Rodriguez, Christian Sapunaru and Andre Castro will return to the squad, with Ruben Micael absent along with Rafa, Ukra and Fernando.
Turkish club Besiktas play host to a Rapid Vienna side that has struggled since they produced the shock of the final qualification round when they dumped out Aston Villa.
Besiktas are understandably in good spirits ahead of the Austrian visit.
CSKA Sofia vs Porto Preview
Besiktas vs Rapid Vienna Preview